Patients w/ bilateral renal artery stenosis or stenosis of an artery to a single kidney, aortic valve stenosis & hypertrophic obstructive cardiomyopathy; heart failure. Symptomatic hypotension may occur. Porphyria. Hepatic impairment. Severe renal impairment. Elderly.
May antagonize effect w/ NSAIDs. May reduce antihypertensive effect w/ sympathomimetics. May elevate serum K w/ K-sparing diuretics. May produce additive antihypertensive & antianginal effects w/ SL nitroglycerin, long-acting nitrates, β-blockers or other anti-anginal agents.
C09DB06 - losartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.
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